Anti-Angiogenic Therapy in Ophthalmology (Essentials in by Andreas Stahl

By Andreas Stahl

This e-book presents a concise evaluation over the pathology of retinal angiogenic illnesses and explains why anti-angiogenic remedy is valuable in such a lot of sufferers. The reader is guided throughout the a variety of scientific symptoms for anti-angiogenic treatment and made conscious of its benefits in addition to present demanding situations and barriers. it really is defined how, seeing that its creation for the therapy of exudative age-related macular degeneration in 2006, anti-angiogenic remedy has revolutionized the way we deal with a number of ocular illnesses. the entire authors are validated specialists of their respective fields who percentage their huge wisdom and scientific event with the reader. This e-book is either a worthwhile advent to anti-angiogenic remedy in ophthalmology and a daily better half for all ophthalmologists seeing sufferers with essentially the most frequent retinal diseases.

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N Engl J Med. 2011;364(20):1897–908. 1056/ NEJMoa1102673. Martin DF, Maguire MG, Fine SL, Ying GS, Jaffe GJ, Grunwald JE, Toth C, Redford M, Ferris 3rd FL. Ranibizumab and bevacizumab for treatment of neovascular age-related macular degeneration: twoyear results. Ophthalmology. 2012;119(7):1388–98. 053. S0161-6420(12)00321-1 [pii]. Martinez-Castellanos MA, Schwartz S, Hernandez-Rojas ML, Kon-Jara VA, Garcia-Aguirre G, Guerrero-Naranjo JL, Chan RV, Quiroz-Mercado H. Long-term effect of antiangiogenic therapy for retinopathy of prematurity up to 5 years of follow-up.

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Note the rapid reduction in plus disease visible by reduced dilatation and reduced tortuosity of the retinal vessels Despite these caveats, the BEAT-ROP results raised some important points: (1) Bevacizumab is effective in halting neovascular disease progression in ROP in most cases; (2) unlike laser therapy, the avascular retinal areas are not destroyed but may become (partially) vascularized over time. Whether the vessels and underlying neural retina are fully normal is unknown at this point.

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