By Andreas Stahl
This e-book presents a concise evaluation over the pathology of retinal angiogenic illnesses and explains why anti-angiogenic remedy is valuable in such a lot of sufferers. The reader is guided throughout the a variety of scientific symptoms for anti-angiogenic treatment and made conscious of its benefits in addition to present demanding situations and barriers. it really is defined how, seeing that its creation for the therapy of exudative age-related macular degeneration in 2006, anti-angiogenic remedy has revolutionized the way we deal with a number of ocular illnesses. the entire authors are validated specialists of their respective fields who percentage their huge wisdom and scientific event with the reader. This e-book is either a worthwhile advent to anti-angiogenic remedy in ophthalmology and a daily better half for all ophthalmologists seeing sufferers with essentially the most frequent retinal diseases.
Read Online or Download Anti-Angiogenic Therapy in Ophthalmology (Essentials in Ophthalmology) PDF
Similar ophthalmology books
Our desire is to enlighten and inspire these laid low with aniridia and WAGR Syndrome by way of supplying sufferer help and scientific info. there's details to notify mom and dad, lecturers, medical professionals, employers, and the general public approximately aniridia and what it really is wish to reside with it. numerous popular medical professionals give a contribution clinical chapters.
This option of articles from the Encyclopedia of the attention is the 1st single-volume evaluation offering articles at the functionality, biology, body structure, and pathology of the buildings of the ocular outer edge, in addition to the comparable issues and their therapy. The peripheral buildings are implicated in a couple of vital illnesses, together with optic neuritis, thyroid eye ailment, and strabismus.
Those instructions, compiled by way of a panel of clinicians and scientists with a excessive point of craftsmanship, goal to supply readers with the main up to date and entire directions at the remedy and prevention of ocular irritation. the entire strategies are explicitly associated with aiding proof and graded in accordance with the power of that facts and the editors have made each attempt to make sure that chapters are of a continuously excessive methodological caliber.
The thoroughly revised, up to date 3rd version of this acclaimed reference is a entire, present, and carefully illustrated consultant to the analysis and administration of neuro-ophthalmologic issues. Written by means of specialists in neurology, ophthalmology, and otorhinolaryngology, the ebook covers all universal and infrequent stipulations affecting the ocular motor and visible sensory platforms.
- Primary Retinal Detachment: Options for Repair
- 2008-2009 Basic and Clinical Science Course: Section 11: Lens and Cataract (Basic and Clinical Science Course 2008-2009)
- Eye Essentials: Rigid Gas-Permeable Lens Fitting, 1e
- The Meaning of Quantum Theory: A Guide for Students of Chemistry and Physics (Oxford Science Publications)
Extra info for Anti-Angiogenic Therapy in Ophthalmology (Essentials in Ophthalmology)
N Engl J Med. 2011;364(20):1897–908. 1056/ NEJMoa1102673. Martin DF, Maguire MG, Fine SL, Ying GS, Jaffe GJ, Grunwald JE, Toth C, Redford M, Ferris 3rd FL. Ranibizumab and bevacizumab for treatment of neovascular age-related macular degeneration: twoyear results. Ophthalmology. 2012;119(7):1388–98. 053. S0161-6420(12)00321-1 [pii]. Martinez-Castellanos MA, Schwartz S, Hernandez-Rojas ML, Kon-Jara VA, Garcia-Aguirre G, Guerrero-Naranjo JL, Chan RV, Quiroz-Mercado H. Long-term effect of antiangiogenic therapy for retinopathy of prematurity up to 5 years of follow-up.
2006;116:369–77. Wang GL, Semenza GL. Characterization of hypoxiainducible factor 1 and regulation of DNA binding activity by hypoxia. J Biol Chem. 1993a;268:21513–8. Wang GL, Semenza GL. General involvement of hypoxiainducible factor 1 in transcriptional response to hypoxia. Proc Natl Acad Sci U S A. 1993b;90:4304–8. 19 Wang GL, Jiang BH, Rue EA, Semenza GL. Hypoxiainducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. Proc Natl Acad Sci U S A. 1995;92:5510–4.
Note the rapid reduction in plus disease visible by reduced dilatation and reduced tortuosity of the retinal vessels Despite these caveats, the BEAT-ROP results raised some important points: (1) Bevacizumab is effective in halting neovascular disease progression in ROP in most cases; (2) unlike laser therapy, the avascular retinal areas are not destroyed but may become (partially) vascularized over time. Whether the vessels and underlying neural retina are fully normal is unknown at this point.